Sonstiges

 

                                                                  -2023-                                                              IF

C40.

 Helm, M., Bohnsack, M.T., Carell, T., Dalpke, A., Entian, K.-D., Ehrenhofer-Murray, A., Ficner, R., Hammann, C., Höbartner, C., Jäschke, A., Jeltsch, A., Kaiser, S., Klassen, R., Leidel, S.A., Marx, A., Mörl, M., Meier, J.C., Meister, G., Rentmeister, A., Rodnina, M., Roignant, J.-Y., Schaffrath, R., Stadler, P., Stafforst, T., Experience with German Research Consortia in the Field of Chemical Biology of Native Nucleic Acid Modifications, (2023), ACD Chem. Biol., Online ahead of print, Full text  PMID: 37962075

4,0

 

C39.

 Pichot, F., Marchand, V., Helm, M., Motorin, Y., Data Analysis Pipeline for Detection and Quantification of Pseudouridine (ψ) in RNA by HydraPsiSeq, (2023), Methods Mol. Biol., 2624:207-223, Full text  PMID: 36723818

1,4

 

                                                                  -2022-                                                              IF

C38.

 Pichot, F., Marchand, V., Helm, M., Motorin, Y., Machine learning algorithm for precise prediction of 2'-O-methylation (Nm) sites from experimental RiboMethSeq datasets, (2022), Methods. Enzymol, 203:311-321, Full text  PMID: 35314341

1,6

 

C37.

 Marchand, V., Bourguignon-Igel, V., Helm, M., Motorin, Y., Analysis of pseudoridines and other RNA modifications using HydraPsiSeq Protocol. (2022), Methods., 203:383-391, Full text  PMID: 34481083

4,7

 

                                                                  -2021-                                                              IF

C36.

Marchand, V., Bourguignon-Igel, V., Helm, M., Motorin, Y., Mapping of 7-methylguanosine (m7G), 3-methylcytidine (m3C), dihydrouridine (D) and 5-hydroxycytidine (ho5C) RNA modifications by AlkAniline-Seq, (2021), Methods. Enzymol, 658:25-47, Full text

  PMID: 34517949

1,6

 

C35.

Marchand, V., Ayadi, L., Bourguignon-Igel, V., Helm, M., Motorin, Y., AlkAniline-Seq: A Highly Sensitive and Specific Method for Simultaneous Mapping of 7-Methyl-guanosine(m7G) and 3-Methyl-cytosine (m3C) in RNAs by High-Troughput Sequencing. (2021), Methods Mol Biol., 2298:77-95, Full text

  PMID: 34085239

1,2

 

                                                                  -2019-                                                              IF

C34.

Galvanin, A., Ayadi, L., Helm, M., Motorin, Y., Marchand, V., Mapping and Quantification of tRNA 2'-O-Methylation by RiboMethSeq. (2019), Methods Mol Biol., 1870:273-295, Full text

  PMID: 30539563

1,2

 

C33.

 Voigt, M., Fritz, T., Worm, M., Frey, H., Helm, M., Surface Modification of Nanoparticles and Nanovesicles via Click-Chemistry, (2019), Methods Mol Biol., May 31, 2000:235-245, Full text PMID: 31148019

1,2

 

                                                                  -2018-                                                              IF

C32.

Slama, K., Galliot, A., Weichmann, F., Hertler, J., Feederle, R., Meister, G., Helm, M.,
Determination of enrichment factors for modified RNA in MeRIP experiments., (2018), Methods., Okt. 28, S1046-2023(18)30304-9, Full text

  PMID: 30394295

4,7

 

C31.

Jantsch, M., Quattrone, A., O'Connell, M., Helm, M., Frye, M., Macias-Gonzales, M., Ohman, M., Ameres, S., Willems, L., Luks, F., Oulas, A., Vanacova, S., Nielsen, H., Bousquet-Antonelli, C., Motorin, Y., Roignant, J.Y., Balatos, N., Dinnyes, A., Baranov, P., Kelly, V., Lamm, A., Rechavi, G., Pelizzola, M., Liepens, J., Holodnuka Kholodnyuk, I., Zammit, V., Ayers,D., Drablos, F., Dahl, J.A., Bujnicki, J., Jeronimo, C., Almeida, R., Neagu, M., Costache, M., Bankovic, J., Bonovic, B., Kyselovic, J., Valor, L.M., Selbert, S., Pir, P., Demircan, T., Cowling, V., SChäfer, M., Rossmanith, W., Lafontaine, D., David, A., Carre, C., Lyko, F., Schaffrath, R., Schwartz, S., Verdel, A., Klungland, A., Purta, E., Timotijevic, G., Cardona, F., Davalos, A., Ballana, E., O Carroll, D., Ule, J., Fray, R.,
Positioning Europe for the EPITRANSCRIPTOMICS challenge., (2018), RNA Biol., Apr. 19, 1562:3-18, Full text

  PMID: 29671387

4,7

 

                                                                  -2017-                                                              IF

C30.

Helm, M.,  Editorial: RNA modifications - what to read first?, (2017), RNA Biology, 14(9):1087-1088, Full text

  PMID: 28795877

4,7

 

C29.

Thüring, K., Schmid, K., Keller, P., Helm, M., (2017) LC-MS Analysis of Methylated RNA. Methods Mol Biol., 1562:3-18, Full text

 PMID: 28349450

N/A

 

C28.

Marchand, V., Ayadi, L., El Hajj, A., Blanloeil-Oillo, F., Helm, M., Motorin, Y., (2017) High-Throughput Mapping of 2'-O-Me Residues in RNA Using Next-Generation Sequencing (Illumina RiboMethSeq Protocol), Methods Mol Biol., 1562:171-187. Full text

 PMID: 28349461

N/A

 

                                                                  -2016-                                                              IF

C27.

Thüring, K., Schmid, K., Keller, P., Helm, M., (2016) Analysis of RNA modifications by liquid chromatography-tandem mass spectrometry. Methods, Mar. 25, Epub ahead of print. Full text

 PMID: 27020891

3,7

 

C26.

Tserovski, L., Marchand, V., Hauenschild, R., Blanloeil-Oillo, F., Helm, M., Motorin, Y., (2016) High-throughput sequencing for 1-methyladenosine (m1A) mapping in RNA. Methods, Feb. 23, Epub ahead of print, Full text

  PMID: 26922842

 

3,7

-2015-                                                                IF      

C25.

Eigenbrod, T., Keller, P., Kaiser, S., Rimbach, K., Dalpe, A.H., Helm, M., (2015), Recognition of Specified RNA Modifications by the Innate Immune System, Methods in enzymology, 560:73-89, Full text 

 PMID: 26253966

N/A

 

-2014-                                                             IF        

C24.

Spenkuch, F., Domingo, O., Hinze, G., Basché, T., & Helm, M. (2014). Studying RNA Using Single Molecule Fluorescence Resonance Energy Transfer. Handbook of RNA Biochemistry: Second, Completely Revised and Enlarged Edition. (Wiley-VCH). 499-526, Full text

 

N/A

C23.

Turunen, J. J., Pavlova, L. V., Hengesbach, M., Helm, M., Müller, S., Hartmann, R. K., & Frilander, M. J. (2014). RNA ligation. Handbook of RNA Biochemistry: Second, Completely Revised and Enlarged Edition. (Wiley-VCH). 45-88, Full text

 

N/A

C22.

Spenkuch, F., (2013). "How do Pseudouridine Synthases work?". JUnQ, 3, 2, Open Questions, 16-20, Full text

  N/A

-2013-

C21.

Klostermeier, D., Hamman, C. (ed.) & Helm, M. (2014). Chemical approaches to the structural investigation of RNA in solution. RNA Structure and Folding. Berlin, Boston: DE GRUYTER. 51-73, Full text

  

N/A

-2012-

C20.

Helm M., Mörl, M., Stadler, P. F., Hoffmann, S., Hoebartner, C. (2012). "Deep Sequencing. RNA: Deep sequencing is the next step in the RNA revolution." Nachrichten aus der Chemie 60(3): 300-307, Full text

 

N/A

-2011-

C19.

Hammann, C., Hartmann, R. K., Helm, M., Klostermeier, D., Marchfelder, A., Suess, B. & Vörtler, S. (2011). "Regulatory RNAs and beyond." EMBO Rep, Jul.15, 12(8): 751-753, Full text

PMID: 21760614

9,1

C18.

Jäschke, A., Micura, R., Grünweller, A., Hartmann, R. & Helm, M. (2011). "Nukleotid Modifikationen: Wertvoll für Grundlagenforschung und therapeutische Anwendung." Nachrichten aus der Chemie 59: 297-302, Full text

 

N/A

C17.

Meusburger, M.**, Hengesbach, M.** & Helm, M.* (2011). "A post-labeling approach for the characterization and quantification of RNA modifications based on site-directed cleavage by DNAzymes." Methods Mol Biol, 718:259-70, Full text

PMID: 21370054

 

1,3

C16.

Hirsch, M., Kim, I.-H., Järve, A., Fischer, R., Trendelenburg, M. F., Massing, U., Rohr, K. & Helm, M.* (2011). "Tracing of siRNAs Inside Cells by FRET Imaging". RNA Interference Techniques. 58: 141-157.

 

N/A

-2010-

C15.

Hartig, J., Helm, M., Jàƒ¤schke, A., Mayer, G., Micura, R., Schwalbe, H. & Wagenknecht, H.-A. (2010). "Funktionale Nukleinsàƒ¤uren." Nachrichten aus der Chemie 58: 305-309,

Full text

 

N/A

C14.

Tovy, A., Hofmann, B., Helm, M. & Ankri, S.* (2010). "In vitro tRNA methylation assay with the Entamoeba histolytica DNA and tRNA methyltransferase Dnmt2 (Ehmeth) enzyme." J Vis Exp(44), Oct. 19, Full text

PMID: 21048666

  

1,3

C13.

Kim, I. H., Jarve, A., Hirsch, M., Fischer, R., Trendelenburg, M. F., Massing, U., Rohr, K. & Helm, M.* (2009). "FRET imaging of cells transfected with siRNA/liposome complexes." Methods Mol Biol, 606:439-55, Full Text

PMID: 20013414

 

1,3

-2009-

C12.

Helm, M.* (2009). "Einzelmolekül-Biochemie." Nachrichten aus der Chemie 57: 282-286, Full text

  N/A

C11.

Porcher, S. & Helm, M. (2009). "Chemical synthesis of DNA and RNA containing modified nucleotides. ". DNA and RNA Modification Enzymes: Comparative Structure, Mechanism, Functions, Cellular Interactions and Evolution. Grosjean, H. Austin, Landes Bioscience: 550-559.

 

N/A

C10.

Hayrapetyan, A., Seidu-Larry, S. & Helm, M. (2009). "Function of modified nucleosides in RNA stabilization". DNA and RNA Modification Enzymes: Comparative Structure, Mechanism, Functions, Cellular Interactions and Evolution. Grosjean, H. Austin, Landes Bioscience: 586-598.

 

N/A

C9.

Seidu-Larry, S., Porcher, S., Micura, R. & Helm, M.* (2009). "List of available phosphoramidites of modified nucleotides for chemical DNA/RNA synthesis". DNA and RNA Modification Enzymes: Comparative Structure, Mechanism, Functions, Cellular Interactions and Evolution. Grosjean, H. Austin, Landes Bioscience: 629-635.

 

 

N/A

-2008-

C8.

Kobitski, A. Y., Hengesbach, M., Helm, M. & Nienhaus, G. U.* (2008). "RNA Intramolekular Dynamics by Single-molecule FRET, From Computational Biophysics to Systems Biology." NIC Series 40: 253-256.

 

N/A

C7.

Hengesbach, M., Kobitski, A., Voigts-Hoffmann, F., Frauer, C., Nienhaus, G. U. & Helm, M. (2008)*. "RNA intramolecular dynamics by single-molecule FRET." Curr Protoc Nucleic Acid Chem, Sep.,  Chapter 11: Unit 11 12, Full text

PMID: 18819081

 

N/A

-before 2008-

C6.

Weigand, B. S., Zerressen, A., Schlatterer, J. S., Helm, M. & Jàƒschke, A.* (2006). "Catalytically active RNA molecules: tools in organic chemistry". Aptamers, Ribozymes and Desoxyribozymes. Klussmann, S., Wiley VCH: 211-227.

 

N/A

C5.

Jäschke, A., Helm, M., Marx, A.* & Strerath, M. (2005). "Protein-nucleic acid interactions." Nachrichten aus der Chemie 53(3): 277-280, Full text

 

N/A

C4.

Jäschke, A.* & Helm, M. (2003). "RNA sex." Chem Biol, Dez., 10(12):1148-50, Full text

PMID: 14700622

  N/A

C3.

Giege, R., Helm, M. & Florentz, C. (2001). "Classical and Novel Chemical Tools for RNA Structure Probing". RNA. Söll, D., Nishimura, S. & Moore, P. Oxford, Pergamon Press: 71-89.

 

N/A

C2.

Florentz, C., Brule, H., Helm, M. & Giege, R. (1999). "Structural studies of human mitochondrial tRNAs". Mitochondrial Diseases. Lestienne, P. Heidelberg, Springer Verlag: 59-72.

 

N/A

C1.

Giege, R., Helm, M. & Florentz, C. (1999). "Chemical and enzymatic Probing of RNA Structure". Comprehensive Natural Product Chemistry. Söll, D. & Nishimura, S. Oxford, Pergamon Press. 6: 63-80.

 

N/A

Patent applications

P2.

Seidu-Larry, S. & Helm, M. (2008) "Reaktive Fluoreszenzfarbstoffe und Leuko-Fluoreszenzfarbstoffe auf Xanthenbasis und Verfahren zur Herstellung derselben".

 

N/A

P1.

Berger, R., Helm, M. & Saurenbach, F. (2006) "Micro-electromechanical sensor device". 06007850.8, E. P. A. & U.S. Ser. No. 11/786.

 

N/A

Textbook

T1.

Helm, M. & Wölfl, S. (2006). "Instrumentelle Bioanalytik", Wiley VCH. 230 Pages

  N/A