| -2017- |
IF |
| 91. |
Helm, M., Aschenbrenner, J., Werner, S., Marchand, V., Adam, M., Motorin, Y., Marx, A., Engineering of a DNA polymerase for direct m6A sequencing., (2017), Angew Chem Int Ed Engl., Nov. 8, Epub ahead of print, Full Text |
PMID: 29115744 |
12,0 |
| 90. |
Boccaletto, P., Machnicka, M.A., Purta, E., Piatkowski, P., Baginski, B., Wirecki, T.K., de Crécy-Lagard, V., Ross, R., Limbach, P.A., Kotter, A., Helm, M., Bujnicki, J.M., MODOMICS: a database of RNA modification Pathways. 2017 update., (2017), Nucleic Acid Research., Nov. 2, Epub ahead of print, Full Text |
PMID: 29106616 |
10,2 |
| 89. |
Negwer, I., Hirsch, M., Kaloyanova, S., Brown, T., Peneva, K., Butt, H.J., Koynov, K., Helm, M., Modulation of Mitochondriotropic Properties of Cyanine Dyes by in Organello Copper-Free Click Reaction., (2017), Chembiochem., Sep. 19, 18(18):1814-1818, Full Text |
PMID: 28704573 |
2,8 |
| 88. |
Weber, B., Kappel, C., Scherer, M., Helm, M., Bros. M., Grabbe, S., Barz, M., PeptoSomes for Vaccination: Combining Antigen and Adjuvant in Polypept(o)ide-Based Polymersomes., (2017), Macromol Biosci., Jul. 31, 17(10), Full Text |
PMID: 28759159 |
3,3 |
| 87. |
Legrand, C., Tuorto, F., Hartmann, M., Liebers, R., Jacob, D., Helm, M., Lyko, F., Statistically robust methylation calling for whole-transcriptome bisulfite sequencing reveals distinct methylation patterns for mouse RNAs, (2017), Genome Res., Jul. 6, 27(9):1589-1596, Full text |
PMID: 28684555 |
11,9 |
| 86. |
Schmitt, F.C.F., Freund, I., Weigand, M.A., Helm, M., Dalpke, A.H., Eigenbrod, T., Identification of an optimized 2'-O-methylated tri-nucleotide RNA motif inhibiting Toll-like receptor 7 and 8, (2017), RNA, Jun. 2, 23(9):1344-1351, Full text |
PMID: 28576825 |
4,6 |
| 85. |
Hellmuth, I., Freund, I., Schlöder, J., Seidu-Larry, S., Thüring, K., Slama, K., Langhanki, J., Kaloyanova, S., Eigenbrod, T., Krumb, M., Röhm, S., Peneva K., Opatz, T., Jonuleit, H., Dalpke, A.H., Helm, M., Bioconjugation of Small Molecules to RNA Impedes Its Recognition by Toll-Like Receptor, (2017), 7. Fronti. Immunol., Mar. 24, 8:312, Full text |
DOI: 10.3389/fimmu.2017.00312 |
5,7 |
| 84. |
Schmid, K., Adobes-Vidal, M., Helm, M., Alkyne-Functionalized Coumarin Compound for Analytic and Preparative 4-Thiouridine Labeling, (2017), Bioconjugate Chemistry, Mar. 15, 28(4):1123-1134, Full text |
PMID: 28263563 |
4,5 |
| 83. |
Marchand, V., Pichot, F., Thüring, K., Avadi, L., Freund, I., Dalpke, A., Helm, M., Motorin, Y., Next-Generation Sequencing-Based RiboMethSeq Protocol for Analysis of tRNA 2'-O-Methylation, (2017), Biomolecules, Feb. 9, 7(1), Full text |
PMID: 28208788 |
N/A |
| -2016- |
IF |
| 82. |
Lence, T., Akhtar, J., Bayer, M., Schmid, K., Spindler, K., Ho, CH., Kreim, N., Andrade-Navarro, MA., Poeck, B., Helm, M., Roignant, JY., m6A modulates neuronal functions and sex determination in Drosophila, (2016), Nature, Dec. 8, 540(7632):242-247, Full text |
PMID: 27919077 |
38,2 |
| 81. |
Kaiser, S., Jurkowski, TP., Kellner, S., Schneider, D., Jeltsch, A., Helm, M., The RNA methyltransferase Dnmt2 methylates DNA in the structural context of a tRNA, (2016)RNA Biology, Nov., 7:1-11, Full text |
PMID: 27819523 |
4,1 |
| 80. |
Hauenschild, R., Werner, S., Tserovski, L., Hildebrandt, A., Motorin, Y., Helm, M., CoverageAnalyzer (CAn): A Tool for Inspection of Modification Signatures in RNA Sequencing Profiles, (2016)Biomolecues., Nov. 10, 6(4), Full text |
PMID: 27834909 |
N/A |
| 79. |
Falckenhayn, C., Carneiro, VC., de Mendonça Amarante, A., Schmid, K., Hanna, K., Kang, S., Helm, M., Dimopoulos, G., Fantappié, MR., Lyko, F., Comprehensive DNA methylation analysis of the Aedes aegypti genome, (2016) Sci. Rep., Nov. 2, 6:36444, Full text |
PMID: 27805064 |
5,2 |
| 78. |
Jüdes, A., Bruch, A., Klassen, R., Helm, M., Schaffrath, R., Sulfur transfer and activation by ubiquitin-like modifier system Uba4Urm1 link protein urmylation and tRNA thiolation in yeast, (2016), Microb Cell., Oct. 24, 3(11):554-564, Full text |
PMID: 28357324 |
N/A |
| 77. |
Müller, S., Fritz, T., Gimnich, M., Worm, M., Helm, M., Frey, H., Biodegradable Hyperbranched Polyether-Lipids with In-Chain pH-Sensitive Linkages, (2016) Polym. Chem., Sep. 19, Full text |
DOI: 10.1039/C6PY01308B |
5,7 |
| 76. |
Tserovski, L., Helm, M.,Diastereoselectivity of 5-methyluridine osmylation is inverted inside an RNA chain., (2016)Bioconjugate Chemistry, Aug. 19, 27(9):2188-97, Full text |
PMID: 27540864
|
4,5 |
| 75. |
Fritz, T., Voigt, M., Worm, M., Negwer, I., Müller, SS., Kettenbach, K., Ross, TL., Roesch, F., Koynov, K., Frey, H., Helm, M., Orthogonal Click Conjugation to the Liposomal Surface Reveals the Stability of the Lipid Anchorage as Crucial for Targeting., (2016)Chemistry, Aug. 8, 22(33):11578-82 |
PMID: 27403892
|
5,8 |
| 74. |
Nick, TA., de Oliverira, TE., Pilat, DW., Spenkuch, F., Butt, HJ., Helm, M., Netz, PA., Berger, R., Stability of a Split Streptomycin Binding Aptamer., (2016)The Journal of physical chemistry. B., Jul. 14, 120(27):6479-89 , Full text |
PMID: 27281393
|
3,2 |
| 73. |
Marchand, V., Blanloeil- Oillo, F., Helm, M., Motorin, Y., Illumina-based RiboMethSeq approach for mapping of 2'-O-Me residues in RNA., (2016)Nucleic Acid Research, Jun. 14, 44(16):e135, Full text |
PMID: 27302133
|
9,1 |
| -2015- |
IF |
| 72. |
Kienhöfer, S., Musheev, MU., Stapf, U., Helm, M., Schomacher, L., Niehrs, C., Schäfer, A., (2015) GADD45a physically and functionally interacts with TET1. Differentiation, Nov. 03, 90(1-3):59-68, Full text |
PMID: 26546041
|
3,4 |
| 71. |
Vogt, G., Falckenhayn, C., Schrimpf, A., Schmid, K., Hanna, K., Pantelein, J., Helm, M., Schulz, R., Lyko, F., (2015) The marbled crayfish as a paradigm for saltational speciation by autopolyploidy and parthenogenesis in animals. Biology Open, Oct. 30, 4(11):1583-94, Full Text |
PMID: 26519519
|
2,4 |
| 70. |
Müller, M., Hartmann, M., Schuster, I., Bender, S., Thüring, KL., Helm, M., Katze, JR., Nellen, W., Lyko, F., Ehrenhofer-Murray, AE. (2015) Dynamic modulation of Dnmt2-dependent tRNA methylation by the micronutrient queuine.Nucleic Acids Research, Sep. 30, 43(22):10952-62, Fulltext |
PMID: 26424849
|
9,1 |
| 69. |
Hauenschild, R., Tserovski, L., Schmid, K., Thüring, K., Winz, ML., Sharma, S., Entian, KD., Wacheul, L., Lafontaine, DL., Anderson, J., Alfonzo, J., Hildebrandt, A., Jäschke, A., Motorin, Y., Helm, M., (2015) The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent.Nucleic Acids Research, Sep. 13, 43(20):9950-64, Fulltext |
PMID: 26365242
|
9,1 |
| 68. |
Schmid, K., Thüring, K., Keller, P., Ochel, A., Kellner, S., Helm, M., (2015) Variable presence of 5-methylcytosine in commercial RNA and DNA.RNA Biology, Aug. 14, 12(10):1152-8, Full text |
PMID: 26274337
|
5,0 |
| 67. |
Bourgeois, G., Ney, M., Gaspar, I., Aiqueperse, C., Schaefer, M., Kellner, S., Helm, M., Motorin, Y. (2015) Eukaryotic rRNA Modification by Yeast 5-Methylcytosine-Methyltransferases and Human Proliferation-Associated Antigen p120. PLoS One, Jul. 21, 10(7):e0133321, Fulltext |
PMID: 26196125
|
3,2 |
| 66. |
Shanmugam, R., Fierer, J., Kaiser, S., Helm, M., Jurkowski, T. P., Jeltsch, A. (2015) Cytosine methylation of tRNA-Asp by DNMT2 has a role in translation of proteins containing poly-Asp sequences.CellDiscovery, Jun. 9, 1, 15010, Fulltext |
doi:10.1038/celldisc.2015.10 |
N/A |
| 65. |
Domingo,O., Hellmuth, I., Jaeschke, A., Kreutz, C., Helm, M. (2015) Intermolecular 'cross-torque': the N4-cytosine propargyl residue is rotated to the 'CH'-edge as a result of Watson-Crick interaction. NucleicAcids Research, Apr. 30, 43(11):5275-83, Full text |
PMID: 25934805 |
9,1 |
| 64. |
Hirsch, M. & Helm, M. (2015) Live cell imaging of duplex siRNA intracellular trafficking. NucleicAcids Research, Apr. 13, 43(9):4650-60, Full text |
PMID: 25870407 |
9,1 |
| 63. |
Rimbach, K., Kaiser, S., Helm, M., Dalpke, A.H., Eigenbrod, T. (2015).2'-O-Methylation within Bacterial RNA Acts as Suppressor of TLR7/TLR8 Activation in Human Innate Immune Cells.Journale of innate immunity. Mar. 20, 7(5):482-93, Fulltext |
PMID: 25823462 |
4,4 |
| 62. |
Juedes, A., Ebert, F., Baer, C., Thuering, K. L., Harrer, A., Klassen, R., Helm, M. & Schaffrath, R. (2015).Urmylationand tRNAthiolation functions of ubiquitin-like Uba4 Urm1 systems are conserved from yeast to man. FEBS letters, Mar. 03, 589(8):904-9, Full text |
PMID:25747390 |
3,2 |
| 61. |
Klassen, R., Grunewald, P., Thuering, K. L., Eichler, C., Helm, M., & Schaffrath, R. (2015).Loss of Anticodon Wobble Uridine Modifications Affects tRNALys Function and Protein Levels in Saccharomyces cerevisiae.PLoSONE,Mar 6;10(3):e0119261, Fulltext |
PMID:25747122 |
3,2 |
| 60. |
Abdel-Fattah, W., Jablownski, D., Di Santo, R., Thuering, K.L., Scheidt, V., Hammermeister, A., Have, S. t., Helm, M., Schaffrath, R., Stark, M.J.R. (2015). ”Phosphorylation of Elp1 by Hrr25 Is Required for Elongator-Dependent tRNA Modification in Yeast. PlosGen.Jan 8. 11(1):e1004931. Fulltext |
PMID:25569479 |
7,5 |
| -2014- |
IF |
| 59. |
Krieg, B., Hirsch, M., Scholz, E., Nuhn, L., Tabujew, I., Bauer, Hâ¦.,&Helm, M. (2014).”New Techniques to Assess In Vitro Release of siRNA from Nanoscale Polyplexes. Pharmaceutical Research. Oct 09, 32(6):1957-74, Full text |
PMID:25488263 |
3,4 |
| 58. |
Spenkuch, F., Hinze, G., Kellner, S., Kreutz, C., Micura, R., Basché, T. & Helm, M. (2014).”Dye label interference with RNA modification reveals 5-fluorouridine as non-covalent inhibitor. NucleicAcids Research. Oct 09, 42(20):12735-45, Full text |
PMID:25300485 |
9,1 |
| 57. |
Kellner, S., Ochel, A., Thüring, K., Spenkuch, F., Neumann, J., Sharma, S., Entian, K.D., Schneider, D. & Helm, M. (2014).”Absolute and relative quantification of RNA modifications via biosynthetic isotopomers. NucleicAcids Research. Aug 16., 42(18):e142, Full text. |
PMID:25129236 |
9,1 |
| 56. |
Blanco, S., Dietmann, S., Flores, J.V., Hussain, S., Kutter, C., Humphreys, P., Lukk, M., Lombard, P., Treps, L. Popis, M., Kellner, S., Hölter, S.M., Garret, L., Wurst, W., Becker, L., Klopstock, T., Fuchs, H., Gailus-Durner, V., Hrabe de Angelis, M., Karadottir, R.T., Helm, M., Ule, J., Gleeson, J.G., Odom, D.T., Frye, M. (2014).”Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders. TheEMBO Journal, Jul 25., 33(18):2020-39, Full text. |
PMID: 25063673 |
10,4 |
| 55. |
Kaiser, S., Rimbach, K., Eigenbrod, T., Dalpke, A.H. & Helm, M. (2014)."A modified dinucleotide motif specifies tRNA recognition by TLR7." RNA Sep.20(9):1351-5, Full text |
PMID:25051971 |
4,9 |
| 54. |
Fritz, T. Hirsch, M. Richter, F.C., Müller, S.S., Hofmann, A.M., Rusitzka, K.A., Markl, J., Massing, U., Frey, H. Helm, M. (2014)."Click modification of multifunctional liposomes bearing hyperbranched polyether chains." Biomacromolecules, Jul 14., 15(7):2440-8, Full text. |
PMID: 24805163 |
5,8 |
| 53. |
KotaskovaM., Osman Oglou O., Helm, M. (2014) "Synthesis of new asymmetric xanthene dyes via catalyst-free SNAr with sulfur nucleophiles" Organic & Biomolecular Chemistry, Jun 21., 12(23):3816-20, Full text. |
PMID: 24802552 |
3,6 |
| 52. |
Shanmugam, R., Aklujkar, M., Schäfer, M., Reinhardt, R., Nickel, O., Reuter, G., Lovley, D.R., Ehrenhofer-Murray, A., Nellen, W., Ankri, S., Helm, M. et al.(2014). "The Dnmt2 RNA methyltransferase homolog of Geobactersulfurreducens specifically methylatestRNA-Glu."Nucleic Acids Research, Apr 7., 42(10):6487-96, Full text. |
PMID: 24711368 |
9,1 |
| 51. |
Tabujew, I., Freidel, C., Krieg, B., Helm, M., Koynov, K., Müllen, K., Peneva, K. (2014). "The Guanidinium Group as a Key Part of Water-Soluble Polymer Carriers for siRNA Complexation and Protection against Degradation." Macromolecular rapid communications, Apr 4.,35(13):1191-7, Full Text. |
PMID: 24700561 |
4,9 |
| 50. |
Buchhaupt, M., Sharma,S., Kellner, S., Oswald, S.,Paetzold, M., Pfeifer, C., Watzinger, P., Schraeder, J., Helm, M., Entian, K.D.(2014). "Partial Methylation at Am100 in 18S rRNA of Baker's Yeast Reveals Ribosome Heterogeneity on the Level of Eukaryotic rRNA Modification." PLoSOne, Feb 28, 9(2):e89640, Full text. |
PMID: 24586927 |
3,2 |
| 49. |
Kellner, S., Neumann, J., Rosenkranz, D., Lebedeva, S., Ketting, R.F., Zischler, H., Schneider, D., & Helm, M.*(2014). "Profiling of RNA modifications by multiplexed stable isotope labelling." ChemicalCommunications.(Cambridge, England), Apr 4., 50(26):3516-8, Full text |
PMID: 24567952 |
6,8 |
| -2013- |
IF |
| 48. |
Kellner, S., Kollar, L. B., Ochel, A., Ghate, M. & Helm, M. (2013). "Structure-Funct ion Relationship of Substituted Bromomethylcoumarins in Nucleoside Specificity of RNA Alkylation." PLoSOne. (Public Library of science), Jul 3., 8(7):e67945, Full text |
PMID: 23844135 |
3,2 |
| 47. |
Machnicka, M. A., Milanowska, K., Osman Oglou, O., Purta, E., Kurkowska, M., Olchowik, A., Januszewski, W., Kalinowski, S., Dunin-Horkawicz, S., Rother, K., Helm, M., Bujnicki, J. M. & Grosjean, H. (2012). "MODOMICS: a database of RNA modification pathways--2012 update." Nucleic Acids Research, Oct 30, 41(Database issue):D262-7, Full text |
PMID: 23118484 |
9,1 |
| -2012- |
IF |
| 46. |
Seidu-Larry, S., Krieg, B., Hirsch, M., Helm, M. & Domingo, O. (2012). "A modified guanosine phosphoramidite for click functionalization of RNA on the sugar edge." ChemicalCommunications (Cambridge, England), Nov 18., 48(89):11014-6, Full text |
PMID: 23037931 |
6,8 |
| 45. |
Tuorto, F., Liebers, R., Musch, T., Schaefer, M., Hofmann, S., Kellner, S., Frye, M., Helm, M., Stoecklin, G. & Lyko, F. (2012)."RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis." Nature Structural & Molecular Biology. Sep, 19(9):900-5, Full Text |
PMID:22885326 |
13,3 |
| 44. |
Jurkowski, T. P., Shanmugam, R., Helm, M. & Jeltsch, A. (2012)."Mapping the tRNA Binding Site on the Surface of Human DNMT2 Methyltransferase." Biochemistry, Jun 5., 51(22):4438-44, Full text |
PMID: 22591353 |
3,0 |
| 43. |
Sencilo, A., Paulin, L., Kellner, S., Helm, M. & Roine, E. (2012). "Related haloarchaeal pleomorphic viruses contain different genome types." Nucleic Acids Research, Jul, 40(12):5523-34, Full Text |
PMID: 22396526 |
9,1 |
| 42. |
Nuhn, L., Hirsch, M., Krieg, B., Koynov, K., Fischer, K., Schmidt, M., Helm, M. & Zentel, R. (2012)."Cationic Nanohydrogel Particles as Potential siRNA Carriers for Cellular Delivery." ACS Nano, Mar 27., 6(3):2198-214, Full text |
PMID: 22381078 |
12,9 |
| 41. |
Gehrig, S., Eberle, M. E., Botschen, F., Rimbach, K., Eberle, F., Eigenbrod, T., Kaiser, S., Holmes, W. M., Erdmann, V. A., Sprinzl, M., Bec, G., Keith, G., Dalpke, A. H. & Helm, M.(2012)."Identification of modifications in microbial, native tRNA that suppress immunostimulatory activity." The Journal of Experimental Medicine, Feb 13., 209(2):225-33, Full text |
PMID: 22312113 |
12,5 |
| 40. |
Hirsch, M., Strand, D. & Helm, M.(2012)."Dye selection for live cell imaging of intact siRNA." BiologicalChemistry , Jan, 393(1-2):23-3, Full text |
PMID: 22628296 |
3,3 |
| -2011- |
| 39. |
Kobitski, A. Y., Hengesbach, M., Seidu-Larry, S., Dammertz, K., Chow, C. S., van Aerschot , A., Nienhaus, G. U. & Helm, M. (2011). "Single-Molecule FRET Reveals a Cooperative Effect of Two Methyl Group Modifications in the Folding of Human Mitochondrial tRNA(Lys)."Chemistry & Biology , Jul 19., 18(7):928-36, Full text |
PMID: 21802013 |
6,7 |
| 38. |
Kellner, S., Seidu-Larry, S., Burhenne, J., Motorin, Y. & Helm, M. (2011). "A multifunctional bioconjugate module for versatile photoaffinity labeling and click chemistry of RNA."NucleicAcids Research, Sep 1., 39(16):7348-60, Full text |
PMID: 21646334 |
|
9,1 |
| 37. |
Nguyen, T. H., Steinbock, L. J., Butt, H. J., Helm, M. & Berger, R. (2011). "Measuring single small molecule binding via rupture forces of a split aptamer." Journal of the American ChemicalSociety , Feb 23., 133(7):2025-7, Full text |
PMID: 21287983 |
12,1 |
| 36. |
Dammertz, K., Hengesbach, M., Helm, M., Nienhaus, G. U. & Kobitski, A. Y. (2011). "Single-molecule FRET studies of counterion effects on the free energy landscape of human mitochondriallysine tRNA." Biochemistry , Apr 19., 50(15):3107-15, Full text |
PMID: 21375355 |
3,0 |
| 35. |
Motorin, Y., Burhenne, J., Teimer, R., Koynov, K., Willnow, S., Weinhold, E. & Helm, M. (2011). "Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling." Nucleic Acids Research , Mar, 39(5):1943-5, Full text |
PMID: 21037259 |
9,1 |
| -2010- |
| 34. |
Schaefer, M., Pollex, T., Hanna, K., Tuorto, F., Meusburger, M., Helm, M. & Lyko, F. (2010). "RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage." Genes & Development , Aug 1., 24(15):1590-5, Full Text |
PMID: 20679393 |
10,8 |
| 33. |
Hengesbach, M., Voigts-Hoffmann, F., Hofmann, B. & Helm, M. (2010). "Formation of a stalled early intermediate of pseudouridine synthesis monitored by real-time FRET." RNA, Mar, 16(3):610-2, Full Text |
PMID: 20106954 |
4,9 |
| 32. |
Tovy, A., Siman Tov, R., Gaentzsch, R., Helm, M. & Ankri, S. (2010). "A new nuclear function of the Entamoebahistolytica glycolytic enzyme enolase: the metabolic regulation of cytosine-5 methyltransferase 2 (Dnmt2) activity." PLoSPathogens , Feb 19., 6(2):e1000775, Full text |
PMID: 20174608 |
7,6 |
| -2009- |
| 31. |
Fuest, C., Bankstahl, M., Winter, P., Helm, M., Pekcec, A. & Potschka, H. (2009). "In vivo down-regulation of mouse brain capillary P-glycoprotein: a preliminary investigation." NeuroscienceLetters , Oct 16., 464(1):47-51, Full text |
PMID: 19679165 |
2,0 |
| 30. |
Hayrapetyan, A., Grosjean, H. & Helm, M. (2009). "Effect of a quaternary pentamine on RNA stabilization and enzymatic methylation." BiologicalChemistry , Sep, 390(9):851-6, Full text |
PMID: 19558320 |
3,3 |
| 29. |
Hirsch, M., Ziroli, V., Helm, M. & Massing, U. (2009). "Preparation of small amounts of sterile siRNA-liposomes with high entrapping efficiency by dual asymmetric centrifugation (DAC)." Journal of Controlled Release , Apr 2.,135(1):80-8, Full text |
PMID: 19124051 |
7,7 |
| -2008- |
| 28. |
Jurkowski, T. P., Meusburger, M., Phalke, S., Helm, M., Nellen, W., Reuter, G. & Jeltsch, A. (2008). "Human DNMT2 methylatestRNA(Asp) molecules using a DNA methyltransferase-like catalytic mechanism." RNA , Aug, 14(8):1663-70, Full text |
PMID: 18567810 |
4,9 |
| 27. |
Kobitski, A. Y., Hengesbach, M., Helm, M. & Nienhaus, G. U. (2008). "Sculpting an RNA conformational energy landscape by a methyl group modification--a single-molecule FRET study." AngewandteChemie (International Ed in Englisch) 47(23):4326-30, Full text |
PMID: 18449867 |
11,3 |
| 26. |
Steinbock, L. J. & Helm, M. (2008). "Wavelength dependence of photoinducedmicrocantilever bending in the UV-VIS range." Sensors 8(1):23-34, Full text |
doi:10.3390/s8010023 |
2,3 |
| 25. |
Hengesbach, M., Meusburger, M., Lyko, F. & Helm, M. (2008). "Use of DNAzymes for site-specific analysis of ribonucleotide modifications." RNA , Jan, 14(1):180-7, Full text |
PMID: 17998290 |
4,9 |
| -2007- |
| 24. |
Voigts-Hoffmann, F., Hengesbach, M., Kobitski, A. Y., van Aerschot, A., Herdewijn, P., Nienhaus, G. U. & Helm, M. (2007). "A methyl group controls conformational equilibrium in human mitochondrial tRNA(Lys)." Journal of the American Chemical Society, Nov 7., 129(44):13382-3, Full text |
PMID: 17941640 |
12,1 |
| 23. |
Järve, A., Müller, J., Kim, I. H., Rohr, K., MacLean, C., Fricker, G., Massing, U., Eberle, F., Dalpke, A., Fischer, R., Trendelenburg, M. F. & Helm, M. (2007). "Surveillance of siRNA integrity by FRET imaging." Nucleic Acids Research, 35(18):e124, Full text |
PMID: 17890733 |
9,1 |
| 22. |
Wehrmeister, J., Fuss, A., Saurenbach, F., Berger, R. & Helm, M. (2007). "Readout of micromechanical cantilever sensor arrays by Fabry-Perot interferometry." TheReview of ScientificInstruments, Oct, 78(10):104105, Full text |
PMID: 17979440 |
1,6 |
| 21. |
Kobitski, A. Y., Nierth, A., Helm, M., Jaschke, A. & Nienhaus, G. U. (2007). "Mg2+-dependent folding of a Diels-Alderase ribozyme probed by single-molecule FRET analysis." NucleicAcids Research, 35(6):2047-5, Full text |
PMID: 17344321 |
9,1 |
| -2006- |
| 20. |
Maniura-Weber, K., Helm, M., Engemann, K., Eckertz, S., Mollers, M., Schauen, M., Hayrapetyan, A., von Kleist-Retzow, J. C., Lightowlers, R. N., Bindoff, L. A. & Wiesner, R. J. (2006). "Molecular dysfunction associated with the human mitochondrial 3302A>G mutation in the MTTL1 (mt-tRNALeu(UUR)) gene." NucleicAcids Research 34(22):6404-15, Full text |
PMID: 17130166 |
9,1 |
| -2005- |
| 19. |
Möllers, M., Maniura-Weber, K., Kiseljakovic, E., Bust, M., Hayrapetyan, A., Jaksch, M., Helm, M., Wiesner, R. J. & von Kleist-Retzow, J. C. (2005). "A new mechanism for mtDNA pathogenesis: impairment of post-transcriptional maturation leads to severe depletion of mitochondrial tRNASer(UCN) caused by T7512C and G7497A point mutations." Nucleic Acids Research , Sep 30., 33(17):5647-58, Full text |
PMID: 16199753 |
9,11 |
| 18. |
Kurschat, W. C., Müller, J., Wombacher, R. & Helm, M. (2005). "Optimizing splinted ligation of highly structured small RNAs." RNA , Dec, 11(12):1909-14, Full text |
PMID: 16251384 |
4,9 |
| 17. |
Helm, M., Petermeier, M., Ge, B., Fiammengo, R. & Jäschke, A. (2005). "Allosterically activated Diels-Alder catalysis by a ribozyme." Journal of the American ChemicalSociety , Aug 3, 127(30):10492-3, Full text |
PMID: 16045328 |
12,1 |
| 16. |
Helm, M., Servant, J. J., Saurenbach, F. & Berger, R. (2005). "Read-out of micromechanical cantilever sensors by phase shifting interferometry." Applied Physics Letters 87(6). |
doi:10.1063/ 1.2008358 |
3,3 |
| -2004- |
| 15. |
Sissler, M., Helm, M., Frugier, M., Giege, R. & Florentz, C. (2004). "Aminoacylation properties of pathology-related human mitochondrial tRNA(Lys) variants." RNA, May, 10(5):841-53 |
PMID: 15100439 |
4,9 |
| 14. |
Helm, M.& Attardi, G. (2004). "Nuclear control of cloverleaf structure of human mitochondrial tRNA(Lys)." Journal of MolecularBiology , Mar 26., 337(3):545-60, Full text |
PMID: 15019776 |
3,0 |
| 13. |
Asin-Cayuela, J., Helm, M. & Attardi, G. (2004). "A monomer-to-trimer transition of the human mitochondrial transcription termination factor (mTERF) is associated with a loss of in vitro activity." Journal of BiologicalChemistry , Apr 9., 279(15):15670-7, Full text |
PMID: 14744862 |
4,6 |
| -2001- |
| 12. |
Schiffer, S., Helm, M., Theobald-Dietrich, A., Giege, R. & Marchfelder, A. (2001). "The plant tRNA 3' processing enzyme has a broad substrate spectrum." Biochemistry , Jul 27., 40(28):8264-72, Full text |
PMID: 11444972 |
3,0 |
| 11. |
Helm, M., Kopka, M. L., Sharma, S. K., Lown, J. W. & Giege, R. (2001). "RNase activity of a DNA minor groove binder with a minimalist catalytic motif from RNase A." Biochemical andBiophysical Research Communications , Mar, 281(5):1283-90, Full text |
PMID: 11243875 |
2,3 |
| -2000- |
| 10. |
Helm, M., Brule, H., Friede, D., Giege, R., Putz, D. & Florentz, C. (2000). "Search for characteristic structural features of mammalian mitochondrial tRNAs." RNA , Oct, 6(10):1356-7, Full text |
PMID: 11073213 |
4,9 |
| -1999- |
| 9. |
Helm, M., Giege, R. & Florentz, C. (1999). "A Watson-Crick base-pair-disrupting methyl group (m1A9) is sufficient for cloverleaf folding of human mitochondrial tRNALys." Biochemistry , Oct 5., 38(40):13338-46, Full text |
PMID: 10529209 |
3,0 |
| 8. |
Vlasov, A. V., Helm, M., Naumov, V. A., Breusov, A. A., Buneva, V. N., Florentz, C., Giege, R. & Nevinskii, G. A. (1999). "[Features of tRNA hydrolysis by autoantibodies from blood serum of patients with certain autoimmune and virus diseases]." MolekuliarnaiaBiologiia (Mosk) , Sep -Oct, 33(5):866-72 |
PMID: 10579192 |
N/A |
| 7. |
Vlassov, A. V., Helm, M., Florentz, C., Naumov, V. A., Breusov, A. A., Buneva, V. N., Giege, R. & Nevinsky, G. A. (1999). "Variability of Substrate Specificity of Serum Antibodies Obtained from Patients with Different Autoimmune and Viral Diseases in Reaction of tRNA Hydrolysis." RussianJournal of Immunologie , Apr, 4(1):25-32 |
PMID: 12687113 |
N/A |
| 6. |
Helm, M., Brule, H., Giege, R. & Florentz, C. (1999). "More mistakes by T7 RNA polymerase at the 5' ends of in vitro-transcribed RNAs." RNA , May, 5(5):618-21, Full text |
PMID: 10334331 |
4,9 |
| 5. |
Helm, M., Florentz, C., Chomyn, A. & Attardi, G. (1999). "Search for differences in post-transcriptional modification patterns of mitochondrial DNA-encoded wild-type and mutant human tRNALys and tRNALeu(UUR)." NucleicAcids Research , Feb 1., 27(3):756-63, Full text |
PMID: 9889270 |
9,1 |
| -1998- |
| 4. |
Degoul, F., Brule, H., Cepanec, C., Helm, M., Marsac, C., Leroux, J., Giege, R. & Florentz, C. (1998). "Isoleucylation properties of native human mitochondrial tRNAIle and tRNAIle transcripts. Implications for cardiomyopathy-related point mutations (4269, 4317) in the tRNAIle gene." Human Molecular Genetics , Mar, 7(3):347-54, Full text |
PMID: 9466989 |
6,4 |
| 3. |
Vlassov, A., Florentz, C., Helm, M., Naumov, V., Buneva, V., Nevinsky, G. & Giege, R. (1998). "Characterization and selectivity of catalytic antibodies from human serum with RNase activity." NucleicAcids Research, Dec 1., 26(23):5243-50, Full text |
PMID: 9826744 |
9,1 |
| 2. |
Frugier, M., Helm, M., Felden, B., Giege, R. & Florentz, C. (1998). "Sequences outside recognition sets are not neutral for tRNAaminoacylation. Evidence for nonpermissive combinations of nucleotides in the acceptor stem of yeast tRNAPhe." TheJournal of BiologicalChemistry , May 8., 273(19):11605-10, Full text |
PMID: 9565578 |
4,8 |
| 1. |
Helm, M., Brule, H., Degoul, F., Cepanec, C., Leroux, J. P., Giege, R. & Florentz, C. (1998). "The presence of modified nucleotides is required for cloverleaf folding of a human mitochondrial tRNA." NucleicAcids Research ,Apr 1., 26(7):1636-43, Full text |
PMID: 9512533 |
9,1 |